![]() Patients’ characteristics, suspected vaccines, and AEFI description were collected. Methods: A retrospective study was performed on suspected AEFI reports for children and adults who received any form of vaccinations, collected in Tuscany, Italy, between 1 January and 31 December 2017. Thus, the aims of the present study were to characterize AEFI in general population (all age groups), in terms of frequency, preventability, and seriousness and to define predictors of their seriousness in children. 9Meyer Children’s Hospital, Florence, Italyīackground: The concern for adverse events following immunization (AEFI) and anti-vaccination movements that lacked scientific evidence-based supports may reduce vaccine uptake in the general population.8Department of Pediatric Immunology, University of Florence, Florence, Italy.7Epidemiology Unit, Department of Prevention, Local Health Unit Tuscany Centre, Florence, Italy. ![]() 6Department of Health Sciences, University of Florence, Florence, Italy.5CiaoLapo, Charity for Healthy Pregnancy, Stillbirth and Perinatal Grief Support, Prato, Italy.4Centre of Pharmacovigilance, University Hospital of Siena, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.3Unit of Adverse Drug Reactions Monitoring, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.2Tuscan Regional Centre of Pharmacovigilance, Florence, Italy.1Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Florence, Italy.Niccolò Lombardi 1† Giada Crescioli 1† Alessandra Bettiol 1 Marco Tuccori 2,3 Marco Rossi 2,4 Roberto Bonaiuti 1 Claudia Ravaldi 5,6 Miriam Levi 7 Alessandro Mugelli 1 Silvia Ricci 8,9 Francesca Lippi 8,9 Chiara Azzari 6,8,9 Paolo Bonanni 6 Alfredo Vannacci 1,2,5*
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